The Department is led by the Director, who represents the structure for all legal purposes and guarantees autonomy and cultural unity.
In order to fulfill its institutional duties, the Department has organisational and administrative autonomy regarding all expenditure as well as contractual and conventional measures which concern it directly, with regard to both public and private subjects, in compliance with current legislation and excluding administrative measures of a general nature or those which are related to issues reserved for other bodies as per the Statute of Sapienza.
The departmental bodies are: the Department Board, the Director, the Department Council.

The Department Director is assisted in the management of the Department's activities by the Delegated Administrative Manager, who is responsible for the administrative office and coordinates the administrative-accounting activities.